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An update on PPAR activation by cannabinoids
Some cannabinoids activate the different isoforms of PPARs (α, β and γ), as shown through the use of reporter gene assays, binding studies, selective antagonists and knockout studies. Activation of all isoforms, but primarily PPARα and γ, mediates some (but not all) of the analgesic, neuroprotective...
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Publicado en: | Br J Pharmacol |
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Autor Principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882496/ https://ncbi.nlm.nih.gov/pubmed/27077495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13497 |
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