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NF-κB Functions in Tumor Initiation by Suppressing the Surveillance of Both Innate and Adaptive Immune Cells

NF-κB is considered a major contributor to tumor development, but how this factor functions in the initial stages of oncogenesis is not clear. In a model of Ras-induced transformation, we probed NF-κB function as preneoplastic cells formed tumors in mice. As previously shown, the p65 subunit of NF-κ...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Wang, David J., Ratnam, Nivedita M., Byrd, John C., Guttridge, Denis C.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882153/
https://ncbi.nlm.nih.gov/pubmed/25263557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.049
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