LRRK2 Regulates Voltage-Gated Calcium Channel Function

Voltage-gated Ca(2+) (Ca(V)) channels enable Ca(2+) influx in response to membrane depolarization. Ca(V)2.1 channels are localized to the presynaptic membrane of many types of neurons where they are involved in triggering neurotransmitter release. Several signaling proteins have been identified as i...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Bedford, Cade, Sears, Catherine, Perez-Carrion, Maria, Piccoli, Giovanni, Condliffe, Steven B.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876133/
https://ncbi.nlm.nih.gov/pubmed/27242426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00035
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