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Arginase 1 is an innate lymphoid cell-intrinsic metabolic checkpoint controlling type 2 inflammation
Group 2 innate lymphoid cells (ILC2s) regulate tissue inflammation and repair following activation by cell-extrinsic factors including host-derived cytokines. However, the cell-intrinsic metabolic pathways that control ILC2 function are undefined. Here we demonstrate that expression of the enzyme Ar...
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| 出版年: | Nat Immunol |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873382/ https://ncbi.nlm.nih.gov/pubmed/27043409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3421 |
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