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How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release

Synaptic ribbons are large proteinaceous scaffolds at the active zone of ribbon synapses that are specialized for rapid sustained synaptic vesicles exocytosis. A single ribbon‐specific protein is known, RIBEYE, suggesting that ribbons may be constructed from RIBEYE protein. RIBEYE knockdown in zebra...

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Bibliographic Details
Published in:EMBO J
Main Authors: Maxeiner, Stephan, Luo, Fujun, Tan, Alison, Schmitz, Frank, Südhof, Thomas C
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868958/
https://ncbi.nlm.nih.gov/pubmed/26929012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592701
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