Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

BACKGROUND: Aggression, hyperactivity, impulsivity, helplessness and anhedonia are all signs of depressive-like disorders in humans and are often reported to be present in animal models of depression induced by stress or by inflammatory challenges. However, chronic mild stress (CMS) and clinically s...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Couch, Yvonne, Trofimov, Alexander, Markova, Natalyia, Nikolenko, Vladimir, Steinbusch, Harry W., Chekhonin, Vladimir, Schroeter, Careen, Lesch, Klaus-Peter, Anthony, Daniel C., Strekalova, Tatyana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867526/
https://ncbi.nlm.nih.gov/pubmed/27184538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0572-0
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