DNA methylation mediates the effect of exposure to prenatal maternal stress on cytokine production in children at age 13½ years: Project Ice Storm

BACKGROUND: Prenatal maternal stress (PNMS) is an important programming factor of postnatal immunity. We tested here the hypothesis that DNA methylation of genes in the NF-κB signaling pathway in T cells mediates the effect of objective PNMS on Th1 and Th2 cytokine production in blood from 13½ year...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Cao-Lei, Lei, Veru, Franz, Elgbeili, Guillaume, Szyf, Moshe, Laplante, David P., King, Suzanne
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866030/
https://ncbi.nlm.nih.gov/pubmed/27182285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0219-0
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