Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria

Inactivation of Kcc3 in a mixed 129/Sv×C57BL/6 mouse background has been previously found to increase systemic blood pressure (BP) through presumed neurogenic mechanisms. Yet, while this background is generally not considered ideal to investigate the cardiovascular system, KCC3 is also expressed in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garneau, Alexandre P., Marcoux, Andrée-Anne, Noël, Micheline, Frenette-Cotton, Rachelle, Drolet, Marie-Claude, Couet, Jacques, Larivière, Richard, Isenring, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864296/
https://ncbi.nlm.nih.gov/pubmed/27166674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154398
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