Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria

Inactivation of Kcc3 in a mixed 129/Sv×C57BL/6 mouse background has been previously found to increase systemic blood pressure (BP) through presumed neurogenic mechanisms. Yet, while this background is generally not considered ideal to investigate the cardiovascular system, KCC3 is also expressed in...

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Vydáno v:PLoS One
Hlavní autoři: Garneau, Alexandre P., Marcoux, Andrée-Anne, Noël, Micheline, Frenette-Cotton, Rachelle, Drolet, Marie-Claude, Couet, Jacques, Larivière, Richard, Isenring, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864296/
https://ncbi.nlm.nih.gov/pubmed/27166674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154398
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