Age-dependent pancreatic gene regulation reveals mechanisms governing human β-cell function

Intensive efforts are focused on identifying regulators of human pancreatic islet cell growth and maturation to accelerate development of therapies for diabetes. After birth, islet cell growth and function are dynamically regulated; however establishing these age-dependent changes in humans has been...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Arda, H. Efsun, Li, Lingyu, Tsai, Jennifer, Torre, Eduardo A., Rosli, Yenny, Peiris, Heshan, Spitale, Robert C., Dai, Chunhua, Gu, Xueying, Qu, Kun, Wang, Pei, Wang, Jing, Grompe, Markus, Scharfmann, Raphael, Snyder, Michael S., Bottino, Rita, Powers, Alvin C., Chang, Howard Y., Kim, Seung K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864151/
https://ncbi.nlm.nih.gov/pubmed/27133132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.002
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