Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections

The interindividual and intraindividual variabilities in daptomycin pharmacokinetics were investigated in 23 patients (69 pharmacokinetic profiles) who were treated for several months for bone and joint infections. Population daptomycin clearance was significantly influenced by renal function and wa...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Goutelle, Sylvain, Roux, Sandrine, Gagnieu, Marie-Claude, Valour, Florent, Lustig, Sébastien, Ader, Florence, Laurent, Frédéric, Chidiac, Christian, Ferry, Tristan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862545/
https://ncbi.nlm.nih.gov/pubmed/26902764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02597-15
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