Histamine 1 receptor-G(βγ)-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock

BACKGROUND: Recent evidence indicates that histamine, acting on histamine 1 receptor (H1R), resets the circadian clock in the mouse suprachiasmatic nucleus (SCN) by increasing intracellular Ca(2+) concentration ([Ca(2+)](i)) through the activation of Ca(V)1.3 L-type Ca(2+) channels and Ca(2+)-induce...

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Foilsithe in:Mol Brain
Main Authors: Kim, Yoon Sik, Kim, Young-Beom, Kim, Woong Bin, Lee, Seung Won, Oh, Seog Bae, Han, Hee-Chul, Lee, C. Justin, Colwell, Christopher S., Kim, Yang In
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2016
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858891/
https://ncbi.nlm.nih.gov/pubmed/27153809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0227-1
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