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Histamine 1 receptor-G(βγ)-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock
BACKGROUND: Recent evidence indicates that histamine, acting on histamine 1 receptor (H1R), resets the circadian clock in the mouse suprachiasmatic nucleus (SCN) by increasing intracellular Ca(2+) concentration ([Ca(2+)](i)) through the activation of Ca(V)1.3 L-type Ca(2+) channels and Ca(2+)-induce...
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Publié dans: | Mol Brain |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858891/ https://ncbi.nlm.nih.gov/pubmed/27153809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0227-1 |
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