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Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model

PURPOSE: Toll-like receptor 4 (TLR4) alerts cells to the presence of bacteria by initiating an inflammatory response. We hypothesize that disruption of the ocular surface barrier in dry eye enhances TLR4 signaling. This study determined whether dry eye enhances expression of inflammatory mediators i...

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Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Simmons, Ken T., Xiao, Yangyan, Pflugfelder, Stephen C., de Paiva, Cintia S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857831/
https://ncbi.nlm.nih.gov/pubmed/27136463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18396
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