Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model

PURPOSE: Toll-like receptor 4 (TLR4) alerts cells to the presence of bacteria by initiating an inflammatory response. We hypothesize that disruption of the ocular surface barrier in dry eye enhances TLR4 signaling. This study determined whether dry eye enhances expression of inflammatory mediators i...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Simmons, Ken T., Xiao, Yangyan, Pflugfelder, Stephen C., de Paiva, Cintia S.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2016
Subjects:
Cornea
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857831/
https://ncbi.nlm.nih.gov/pubmed/27136463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18396
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