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Quantifying Treatment Benefit in Molecular Subgroups to Assess a Predictive Biomarker

There is an increased interest in finding predictive biomarkers that can guide treatment options for both mutation carriers and non-carriers. The statistical assessment of variation in treatment benefit (TB) according to the biomarker carrier status plays an important role in evaluating predictive b...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Iasonos, Alexia, Chapman, Paul B., Satagopan, Jaya M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856220/
https://ncbi.nlm.nih.gov/pubmed/27141007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2517
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