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MiR-122 Reverses the Doxorubicin-Resistance in Hepatocellular Carcinoma Cells through Regulating the Tumor Metabolism
Doxorubicin (DOX) is one of the most commonly used anticancer drugs in the treatment of hepatoma. However, acquired drug resistance is one of the major challenges for the chemotherapy. In this study, a down-regulation of miR-122 was observed in doxorubicin-resistant Huh7 (Huh7/R) cells compared with...
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Опубликовано в: : | PLoS One |
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Главные авторы: | , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854441/ https://ncbi.nlm.nih.gov/pubmed/27138141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152090 |
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