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MiR-122 Reverses the Doxorubicin-Resistance in Hepatocellular Carcinoma Cells through Regulating the Tumor Metabolism

Doxorubicin (DOX) is one of the most commonly used anticancer drugs in the treatment of hepatoma. However, acquired drug resistance is one of the major challenges for the chemotherapy. In this study, a down-regulation of miR-122 was observed in doxorubicin-resistant Huh7 (Huh7/R) cells compared with...

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Опубликовано в: :PLoS One
Главные авторы: Pan, Chenwei, Wang, Xiaodong, Shi, Keqing, Zheng, Yi, Li, Jie, Chen, Yongping, Jin, Lingxiang, Pan, Zhenzhen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854441/
https://ncbi.nlm.nih.gov/pubmed/27138141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152090
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