MiR-122 Reverses the Doxorubicin-Resistance in Hepatocellular Carcinoma Cells through Regulating the Tumor Metabolism

Doxorubicin (DOX) is one of the most commonly used anticancer drugs in the treatment of hepatoma. However, acquired drug resistance is one of the major challenges for the chemotherapy. In this study, a down-regulation of miR-122 was observed in doxorubicin-resistant Huh7 (Huh7/R) cells compared with...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pan, Chenwei, Wang, Xiaodong, Shi, Keqing, Zheng, Yi, Li, Jie, Chen, Yongping, Jin, Lingxiang, Pan, Zhenzhen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854441/
https://ncbi.nlm.nih.gov/pubmed/27138141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152090
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