In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with poor overall survival. New therapeutic strategies that target specific molecular lesions driving advanced disease are needed. Herein we demonstrate the utility of the chicken chorioallantoic membrane (CAM) assay f...

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Dettagli Bibliografici
Pubblicato in:J Otolaryngol Head Neck Surg
Autori principali: Rudy, Shannon F., Brenner, J. Chad, Harris, Jennifer L., Liu, Jun, Che, Jianwei, Scott, Megan V., Owen, John Henry, Komarck, Christine M., P. Graham, Martin, L. Bellile, Emily, Bradford, Carol R., Prince, Mark EP, Carey, Thomas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845503/
https://ncbi.nlm.nih.gov/pubmed/27117272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40463-016-0140-8
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