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Human somatic cells subjected to genetic induction with six germ line-related factors display meiotic germ cell-like features

The in vitro derivation of human germ cells has attracted interest in the last years, but their direct conversion from human somatic cells has not yet been reported. Here we tested the ability of human male somatic cells to directly convert into a meiotic germ cell-like phenotype by inducing them wi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Medrano, Jose V., Martínez-Arroyo, Ana M., Míguez, Jose M., Moreno, Inmaculada, Martínez, Sebastián, Quiñonero, Alicia, Díaz-Gimeno, Patricia, Marqués-Marí, Ana I., Pellicer, Antonio, Remohí, Jose, Simón, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844986/
https://ncbi.nlm.nih.gov/pubmed/27112843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24956
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