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Combining Phage and Yeast Cell Surface Antibody Display to Identify Novel Cell Type-Selective Internalizing Human Monoclonal Antibodies

Using phage antibody display, large libraries can be generated and screened to identify monoclonal antibodies with affinity for target antigens. However, while library size and diversity is an advantage of the phage display method, there is limited ability to quantitatively enrich for specific bindi...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Bidlingmaier, Scott, Su, Yang, Liu, Bin
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842226/
https://ncbi.nlm.nih.gov/pubmed/26060069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2748-7_3
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