Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin

Histone H3 trimethylation of lysine 9 (H3K9me3) and proteins of the heterochromatin protein 1 (HP1) family are hallmarks of heterochromatin, a state of compacted DNA essential for genome stability and long-term transcriptional silencing. The mechanisms by which H3K9me3 and HP1 contribute to chromati...

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Publicado no:Nat Commun
Main Authors: Hiragami-Hamada, Kyoko, Soeroes, Szabolcs, Nikolov, Miroslav, Wilkins, Bryan, Kreuz, Sarah, Chen, Carol, De La Rosa-Velázquez, Inti A., Zenn, Hans Michael, Kost, Nils, Pohl, Wiebke, Chernev, Aleksandar, Schwarzer, Dirk, Jenuwein, Thomas, Lorincz, Matthew, Zimmermann, Bastian, Walla, Peter Jomo, Neumann, Heinz, Baubec, Tuncay, Urlaub, Henning, Fischle, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838890/
https://ncbi.nlm.nih.gov/pubmed/27090491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11310
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