Acute Fibrinolysis Shutdown after Injury Occurs Frequently and Increases Mortality: A Multicenter Evaluation of 2,540 Severely Injured Patients

BACKGROUND: Fibrinolysis is a physiologic process to maintain microvascular patency by breaking down excessive fibrin clot. Hyperfibrinolysis (HF) is associated with a doubling of mortality. Fibrinolysis shutdown (SD), an acute impairment of fibrinolysis, has been recognized as a risk factor for inc...

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Vydáno v:J Am Coll Surg
Hlavní autoři: Moore, Hunter B, Moore, Ernest E, Liras, Ioannis N, Gonzalez, Eduardo, Harvin, John A, Holcomb, John B, Sauaia, Angela, Cotton, Bryan A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834914/
https://ncbi.nlm.nih.gov/pubmed/26920989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2016.01.006
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