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Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis
The transcriptional regulator PhoP is an essential virulence factor in Mycobacterium tuberculosis, and it presents a target for the development of new anti-tuberculosis drugs and attenuated tuberculosis vaccine strains. PhoP binds to DNA as a highly cooperative dimer by recognizing direct repeats of...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832192/ https://ncbi.nlm.nih.gov/pubmed/27079268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24442 |
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