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Huntington disease: a single-gene degenerative disorder of the striatum
Huntington disease (HD) is an autosomal dominant, neurodegenerative disorder with a primary etiology of striatal pathology. The Huntingtin gene (HTT) has a unique feature of a DNA trinucleotide (triplet) repeat, with repeat length ranging from 10 to 35 in the normal population. Repeat lengths betwee...
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| Published in: | Dialogues Clin Neurosci |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Les Laboratoires Servier
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826775/ https://ncbi.nlm.nih.gov/pubmed/27069383 |
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