T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure

Fructose-1,6-bisphosphatase (FBPase) catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and is a key enzyme of gluconeogenesis and glyconeogenesis and, more generally, of the control of energy metabolism and glucose homeostasis. Vertebrates, and notably Homo sapiens, expre...

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Publicado en:Acta Crystallogr D Struct Biol
Autores principales: Barciszewski, Jakub, Wisniewski, Janusz, Kolodziejczyk, Robert, Jaskolski, Mariusz, Rakus, Dariusz, Dzugaj, Andrzej
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2016
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822563/
https://ncbi.nlm.nih.gov/pubmed/27050133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316001765
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