Sialic Acid Is Required for Neuronal Inhibition by Soluble MAG but not for Membrane Bound MAG

Myelin-Associated Glycoprotein (MAG), a major inhibitor of axonal growth, is a member of the immunoglobulin (Ig) super-family. Importantly, MAG (also known as Siglec-4) is a member of the Siglec family of proteins (sialic acid-binding, immunoglobulin-like lectins), MAG binds to complex gangliosides,...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Al-Bashir, Najat, Mellado, Wilfredo, Filbin, Marie T.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817280/
https://ncbi.nlm.nih.gov/pubmed/27065798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00021
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