Wnt/β-Catenin Regulates the Activity of Epiprofin/Sp6, SHH, FGF, and BMP to Coordinate the Stages of Odontogenesis

Background: We used an in vitro tooth development model to investigate the effects of overactivation of the Wnt/β-catenin pathway during odontogenesis by bromoindirubin oxime reagent (BIO), a specific inhibitor of GSK-3 activity. Results: Overactivating the Wnt/β-catenin pathway at tooth initiation...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Aurrekoetxea, Maitane, Irastorza, Igor, García-Gallastegui, Patricia, Jiménez-Rojo, Lucia, Nakamura, Takashi, Yamada, Yoshihiko, Ibarretxe, Gaskon, Unda, Fernando J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811915/
https://ncbi.nlm.nih.gov/pubmed/27066482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00025
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