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Role of Lipocalin-2 in Thrombin-induced Brain Injury

BACKGROUND AND PURPOSE: Thrombin and lipocalin-2 (LCN2) contribute to intracerebral hemorrhage-induced brain injury. Thrombin-induced brain damage is partially through a thrombin receptor, protease-activated receptor-1 (PAR-1). LCN2 is involved in cellular iron transport and neuroinflammation. The p...

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Bibliographic Details
Published in:Stroke
Main Authors: Mao, Shanshan, Xi, Guohua, Keep, Richard F., Hua, Ya
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811682/
https://ncbi.nlm.nih.gov/pubmed/26869387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.012153
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