The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction

Type XIX collagen is a minor collagen associated with basement membranes. It was isolated for the first time in a human cDNA library from rhabdomyosarcoma and belongs to the FACITs family (Fibril Associated Collagens with Interrupted Triple Helices). Previously, we demonstrated that the NC1 domain o...

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Udgivet i:Oncotarget
Main Authors: Oudart, Jean-Baptiste, Doué, Manon, Vautrin, Alexia, Brassart, Bertrand, Sellier, Christèle, Dupont-Deshorgue, Aurelie, Monboisse, Jean-Claude, Maquart, François-Xavier, Brassart-Pasco, Sylvie, Ramont, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811477/
https://ncbi.nlm.nih.gov/pubmed/26621838
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