APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

The multifunctional cytokine transforming growth factor-β (TGFβ) is produced by several types of cancers, including prostate cancer, and promote tumour progression in autocrine and paracrine manners. In response to ligand binding, the TGFβ type I receptor (TβRI) activates Smad and non-Smad signallin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Song, Jie, Mu, Yabing, Li, Chunyan, Bergh, Anders, Miaczynska, Marta, Heldin, Carl-Henrik, Landström, Marene
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807998/
https://ncbi.nlm.nih.gov/pubmed/26583432
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