Ryanodine receptor sensitivity governs the stability and synchrony of local calcium release during cardiac excitation-contraction coupling

Calcium-induced calcium release is the principal mechanism that triggers the cell-wide [Ca(2+)](i) transient that activates muscle contraction during cardiac excitation-contraction coupling (ECC). Here, we characterize this process in mouse cardiac myocytes with a novel mathematical action potential...

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Bibliographic Details
Published in:J Mol Cell Cardiol
Main Authors: Wescott, Andrew P., Jafri, M. Saleet, Lederer, W.J., Williams, George S.B.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807626/
https://ncbi.nlm.nih.gov/pubmed/26827896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.024
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