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Blinding in randomized controlled trials in general and abdominal surgery: protocol for a systematic review and empirical study

BACKGROUND: Blinding is a measure in randomized controlled trials (RCT) to reduce detection and performance bias. There is evidence that lack of blinding leads to overestimated treatment effects. Because of the physical component of interventions, blinding is not easily applicable in surgical trials...

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Bibliographic Details
Published in:Syst Rev
Main Authors: Probst, Pascal, Grummich, Kathrin, Heger, Patrick, Zaschke, Steffen, Knebel, Phillip, Ulrich, Alexis, Büchler, Markus W., Diener, Markus K.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806514/
https://ncbi.nlm.nih.gov/pubmed/27012940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-016-0226-4
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