Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

Many peroxy-containing secondary metabolites(1,2) have been isolated and shown to provide beneficial effects to human health(3–5). Yet, the mechanisms of most endoperoxide biosyntheses are not well understood. Although endoperoxides have been suggested as key reaction intermediates in several cases(...

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Veröffentlicht in:Nature
Hauptverfasser: Yan, Wupeng, Song, Heng, Song, Fuhang, Guo, Yisong, Wu, Cheng-Hsuan, Her, Ampon Sae, Pu, Yi, Wang, Shu, Naowarojna, Nathchar, Weitz, Andrew, Hendrich, Michael P., Costello, Catherine E., Zhang, Lixin, Liu, Pinghua, Zhang, Yan Jessie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804460/
https://ncbi.nlm.nih.gov/pubmed/26524521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15519
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