miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy

Noncoding RNAs have emerged as important modulators in cardiac development and pathological remodeling. Recently, we demonstrated that regulation of the Gtl2-Dio3 noncoding RNA locus is dependent on the MEF2 transcription factor in cardiac muscle, and that two of its encoded miRNAs, miR-410 and miR-...

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Опубликовано в: :PLoS One
Главные авторы: Clark, Amanda L., Maruyama, Sonomi, Sano, Soichi, Accorsi, Anthony, Girgenrath, Mahasweta, Walsh, Kenneth, Naya, Francisco J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801331/
https://ncbi.nlm.nih.gov/pubmed/26999812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151515
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