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Animal models of myasthenia gravis: utility and limitations
Myasthenia gravis (MG) is a chronic autoimmune disease caused by the immune attack of the neuromuscular junction. Antibodies directed against the acetylcholine receptor (AChR) induce receptor degradation, complement cascade activation, and postsynaptic membrane destruction, resulting in functional r...
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Publicado en: | Int J Gen Med |
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Autores principales: | , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786081/ https://ncbi.nlm.nih.gov/pubmed/27019601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJGM.S88552 |
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