Intestinal phospholipid remodeling is required for dietary lipid uptake and survival on a high-fat diet

Phospholipids are important determinants of membrane biophysical properties, but the impact of membrane acyl chain composition on dietary lipid absorption is unknown. Here we demonstrate that the LXR-responsive phospholipid-remodeling enzyme Lpcat3 modulates intestinal fatty acid and cholesterol abs...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Wang, Bo, Rong, Xin, Duerr, Mark A., Hermanson, Daniel J., Hedde, Per Niklas, Wong, Jinny S., de Aguiar Vallim, Thomas Q., Cravatt, Benjamin F., Gratton, Enrico, Ford, David A., Tontonoz, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785086/
https://ncbi.nlm.nih.gov/pubmed/26833026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.01.001
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