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GEN-27, a Newly Synthetic Isoflavonoid, Inhibits the Proliferation of Colon Cancer Cells in Inflammation Microenvironment by Suppressing NF-κB Pathway

Nonresolving inflammation is one of the consistent features of the tumor microenvironment in the intestine and plays a critical role in the initiation and development of colon cancer. Here we reported the inhibitory effects of GEN-27, a new derivative of genistein, on the inflammation-related colon...

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Опубликовано в: :Mediators Inflamm
Главные авторы: Wang, Yajing, Lu, Ping, Zhang, Weifeng, Du, Qianming, Tang, Jingjing, Wang, Hong, Lu, Jinrong, Hu, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781992/
https://ncbi.nlm.nih.gov/pubmed/27057094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2853040
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