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IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin
Recent studies suggest that tumor-associated macrophage-produced IL-6 is an important mediator within the tumor microenvironment that promotes tumor growth. The activation of IL-6/STAT3 axis has been associated with chemoresistance and poor prognosis of a variety of cancers including colorectal carc...
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Gepubliceerd in: | Mediators Inflamm |
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Hoofdauteurs: | , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Hindawi Publishing Corporation
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4781984/ https://ncbi.nlm.nih.gov/pubmed/27006530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8026494 |
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