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Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas

CD133 has played a pivotal role in the identification and isolation of brain tumor stem cells. The correlation between CD133 expression in tumor tissues with patients survival is still controversial. CD133 expression is determinated by methylation status of the promoter region 1–3. Aberrant methylat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neurooncol
Main Authors: Wu, Xing, Wu, Fenlang, Xu, Dongwen, Zhang, Tao
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781890/
https://ncbi.nlm.nih.gov/pubmed/26757925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-2039-z
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