Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas

CD133 has played a pivotal role in the identification and isolation of brain tumor stem cells. The correlation between CD133 expression in tumor tissues with patients survival is still controversial. CD133 expression is determinated by methylation status of the promoter region 1–3. Aberrant methylat...

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Bibliographic Details
Published in:J Neurooncol
Main Authors: Wu, Xing, Wu, Fenlang, Xu, Dongwen, Zhang, Tao
Format: Artigo
Language:Inglês
Published: Springer US 2016
Subjects:
Laboratory Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781890/
https://ncbi.nlm.nih.gov/pubmed/26757925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-2039-z
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