Nalaganje...
Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities
The RAS/MAPK-signalling pathway is frequently deregulated in non-small cell lung cancer (NSCLC), often through KRAS activating mutations(1-3). A single endogenous mutant Kras allele is sufficient to promote lung tumour formation in mice but malignant progression requires additional genetic alteratio...
Shranjeno v:
| izdano v: | Nature |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780242/ https://ncbi.nlm.nih.gov/pubmed/26909577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16967 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|