The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) and several neurodegenerative disorders known as tauopathies are characterized by misfolding and aggregation of tau protein. Although several studies have suggested the potential of traditional Chinese medicine (TCM) as treatment for neurodegenerative diseases, t...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chang, Kuo-Hsuan, Chen, I-Cheng, Lin, Hsuan-Yuan, Chen, Hsuan-Chiang, Lin, Chih-Hsin, Lin, Te-Hsien, Weng, Yu-Ting, Chao, Chih-Ying, Wu, Yih-Ru, Lin, Jung-Yaw, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778784/
https://ncbi.nlm.nih.gov/pubmed/27013866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S96454
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