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Simple image-based no-wash method for quantitative detection of surface expressed CFTR

Cystic fibrosis (CF) is the most common lethal genetic disease among Caucasians. It is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, which encodes an apical membrane anion channel that is required for regulating the volume and composition of epithelial secretions. Th...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Larsen, Mads Breum, Hu, Jennifer, Frizzell, Raymond A., Watkins, Simon C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773656/
https://ncbi.nlm.nih.gov/pubmed/26361332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.09.006
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