Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor

The pleiotropic role of human secretin (hSCT) validates its potential use as a therapeutic agent. Nevertheless, the structure of secretin in complex with its receptor is necessary to develop a suitable therapeutic agent. Therefore, in an effort to design a three-dimensional virtual homology model an...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Singh, Kailash, Senthil, Vijayalakshmi, Arokiaraj, Aloysius Wilfred Raj, Leprince, Jérôme, Lefranc, Benjamin, Vaudry, David, Allam, Ahmed A., Ajarem, Jamaan, Chow, Billy K. C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773067/
https://ncbi.nlm.nih.gov/pubmed/26930505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149359
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