Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4(+) T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

Background. The immunopathogenesis of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains unclear. We determined the association between pathogen-specific T-cell responses and development of paradoxical TB-IRIS on antiretroviral therapy (ART). Methods. T...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Ravimohan, Shruthi, Tamuhla, Neo, Nfanyana, Kebatshabile, Steenhoff, Andrew P., Letlhogile, Rona, Frank, Ian, MacGregor, Rob Roy, Gross, Robert, Weissman, Drew, Bisson, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
HIV/AIDS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772844/
https://ncbi.nlm.nih.gov/pubmed/26611774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ978
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