RNA disruption is associated with response to multiple classes of chemotherapy drugs in tumor cell lines

BACKGROUND: Cellular stressors and apoptosis-inducing agents have been shown to induce ribosomal RNA (rRNA) degradation in eukaryotic cells. Recently, RNA degradation in vivo was observed in patients with locally advanced breast cancer, where mid-treatment tumor RNA degradation was associated with c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Narendrula, Rashmi, Mispel-Beyer, Kyle, Guo, Baoqing, Parissenti, Amadeo M., Pritzker, Laura B., Pritzker, Ken, Masilamani, Twinkle, Wang, Xiaohui, Lannér, Carita
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765116/
https://ncbi.nlm.nih.gov/pubmed/26911141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2197-1
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