A Mutation in IL4RA Is Associated with the Degree of Pathology in Human TB Patients

The contribution of interleukin- (IL-) 4 receptor-alpha- (Rα-) dependent events in the pathogenesis of tuberculosis (TB) is controversial. We have recently shown IL-13 overexpression in mice to cause recrudescent Mtb replication and centrally necrotizing granulomas strongly resembling pathology of h...

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Publicado en:Mediators Inflamm
Autores principales: Hölscher, Christoph, Heitmann, Lisa, Owusu-Dabo, Ellis, Horstmann, Rolf D., Meyer, Christian G., Ehlers, Stefan, Thye, Thorsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764744/
https://ncbi.nlm.nih.gov/pubmed/26977119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4245028
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