Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells

BACKGROUND: The metabolism of cancer cells is often reprogrammed by dysregulation of metabolic enzymes. Transketolase-like 1 (TKTL1) is a homodimeric transketolase linking the pentose-phosphate pathway with the glycolytic pathway. It is generally silenced at a transcriptional level in somatic tissue...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Jayachandran, Aparna, Lo, Pu-Han, Chueh, Anderly C., Prithviraj, Prashanth, Molania, Ramyar, Davalos-Salas, Mercedes, Anaka, Matthew, Walkiewicz, Marzena, Cebon, Jonathan, Behren, Andreas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763451/
https://ncbi.nlm.nih.gov/pubmed/26907172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2185-5
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars