PcpA promotes higher levels of infection and modulates recruitment of myeloid-derived suppressor cells during pneumococcal pneumonia.()

We used two different infection models to investigate the kinetics of the PcpA-dependent pneumococcal disease in mice. In a bacteremic pneumonia model, we observed a PcpA-dependent increase in bacterial burden in the lungs, blood, liver, BAL and spleens of mice at 24-hrs post infection. This PcpA-de...

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Bibliographic Details
Published in:	J Immunol
Main Authors:	Walker, Melissa M., Novak, Lea, Widener, Rebecca, Grubbs, James Aaron, King, Janice, Hale, Joanetha Y., Ochs, Martina M., Myers, Lisa E., Briles, David E., Deshane, Jessy
Format:	Artigo
Language:	Inglês
Published:	2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4761482/ https://ncbi.nlm.nih.gov/pubmed/26829988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402518
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PcpA promotes higher levels of infection and modulates recruitment of myeloid-derived suppressor cells during pneumococcal pneumonia.()

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